With the Ion Torrent Oncomine Myeloid Assay GX on the Ion Torrent Genexus System, you can get a comprehensive myeloid mutational profile from a single next-generation sequencing (NGS) run and results in just one day. A highly integrated workflow lets you go from specimen to report with only 10 minutes of hands-on time and two user touch points*. It’s never been easier to implement myeloid NGS testing in your lab.
While myeloid molecular testing can be complex and laborious with single-gene assays relying on multiple technologies like Sanger sequencing, FISH and qPCR, the Oncomine Myeloid Assay GX simplifies the biggest challenges, including extended wait times for results.
DNA and RNA profiling with one assay covering all key mutations
Curated gene content associated with major myeloid disorders
Rapid turnaround time – get results for all biomarkers in a single day
Automated workflow with only 10 min. of hands-on time required
Integrated reporting with variants linked to relevant evidence
Simultaneously interrogate DNA mutations and RNA fusion transcripts covering all major myeloid disorders: AML, MPN, MDS, CMML, and JMML. With a single assay, you can profile key targets such as FLT3, TP53, NPM1, IDH1/2, BCR-ABL and PML-RARA, along with many other carefully curated biomarkers. See the gene list.
Start with any common myeloid specimen type, including whole blood, bone marrow, or peripheral blood leukocytes. From there, the Genexus System integrates and automates nucleic acid extraction, purification, quantitation, library preparation, sequencing, and analysis reporting within a single software ecosystem.
The solution lets you process samples as they come in—even just one. Sequence 1-8 myeloid samples per run. The reagents are stable on the instrument for up to two weeks, giving you the flexibility to process additional samples as needed.
Ion Torrent Oncomine Reporter is a curated knowledgebase and reporting software that links biomarkers to relevant evidence and enables custom reporting. These tools help simplify the bioinformatics workflow and enable you to focus on finding the biological meaning of your data.
The use of genomic profiling for myeloid samples has accelerated in recent years due in part to increasing annotation of disease-associated biomarkers.
As this list of relevant biomarkers continues to expand, traditional single-gene testing approaches are becoming infeasible.
In this webinar we'll showcase the latest advancements in myeloid genomic profiling: The Ion Torrent Oncomine Myeloid Assay GX.
Learn how this solution addresses key challenges in myeloid molecular testing and see recent data from the University of Pennsylvania.
For Research Use Only. Not for use in diagnostic procedures. *Specimen-to-report workflow will be available after the Ion Torrent Genexus Purification System and integrated reporting capabilities are added in 2021 with the Genexus 6.4 software upgrade.