Lymphoid malignancies involve the clonal proliferation of one or more B or T cells.
Clonality testing of clinical research samples often uses capillary electrophoresis (CE); but this method has limitations, like missing the clone of interest if there are various clones with sequences of the same size.
NGS overcomes these limitations with higher specificity and sensitivity—an LoD of as low as 10–6—and the ability to provide the sequence of B or T cell receptors for all clones in a sample.
Simplify NGS clone detection with our integrated Ion Reporter™ Software. This fully automated solution comes with unique, interactive visualization tools to streamline interpretation.
