Oncomine Oncology Posters at the

2022 Association for Cancer Research (AACR) Annual Meeting

View all of our scientific posters presented at the 2022 Association For Cancer Research (AACR) Annual Meeting. Or you can select a application area of your interest below.

Tumor Profiling  |   Hematology-oncology  |  Bioinformatics

Tumor Profiling Posters



Detection of gene fusions and exon skipping events in lung FFPE samples with Oncomine Precision Assay on Ion Torrent Genexus System

This poster describes the study of studying known oncogenic fusions and exon skip variants, as well as a method for detection of novel fusion combinations and detection of fusions in a partner agnostic manner.

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Rapid and accurate variant calling of FFPE samples with the Genexus System

This poster demonstrates that the Genexus System is a reliable and fast turnaround solution for sample-to-variant calling results. When used with the Oncomine™ Comprehensive Assay v3 panel, the system provides accurate identification of tumor markers for oncology research.

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Automation meets reliability: use of Oncomine Precision Assay on the Genexus System for accurate identification of cancer biomarkers in FFPE and liquid biopsy samples

This poster demonstrates that the Genexus™ system provides a user-friendly workflow with automated NA purification, quantitation, sample dilution, library preparation, sequencing, and data analysis with minimal hands-on time that can be performed with limited expertise to obtain results within 24 hours.

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High-throughput NGS solutions for detection of oncology variants, gene fusion events, and key oncology research endpoints

This poster contains information that demonstrates the ability to evaluate tumor mutational burden (TMB), microsatellite instability (MSI), loss of heterozygosity (LOH), and homologous recombination repair deficiency (HRD) using the Oncomine Comprehensive Assay Plus run on the Genexus System.

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Hematology-oncology Posters



Analytical performance of a novel next-generation sequencing assay for myeloid MRD

This poster characterizes a comprehensive Myeloid MRD (RUO) assay that reliably identifies DNA mutations and fusions with high sensitivity and provides a new tool for myeloid MRD research.

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Somatic hypermutation analysis of chronic lymphocytic leukemia research samples by DNA or RNA input IGH chain sequencing

This poster describes use of Ion AmpliSeq™ next generation sequencing (NGS) assays for research in IGH chain Somatic Hyper Mutation are evaluated using multiple cohorts of CLL research samples.

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Fully automated sample-to-report NGS workflow for comprehensive genomic profiling of myeloid neoplasms

This poster describes development of a fully automated NGS Myeloid Assay that offers an easy to use sample-to-report workflow and the capability for processing up to 8 samples per day.

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Evaluation of multiple myeloma research samples by analysis of multiple B cell receptor targets in a single NGS assay

This poster describes results of B cell repertoire analysis in multiple myeloma samples by next-generation sequencing (NGS) through use of the Oncomine BCR Pan-Clonality Assay.

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Bioinformatics Poster



Shannon entropy of mutational signatures predicts sensitivity of signature detection in targeted sequencing

This poster describes the complexity of the COSMIC mutational signatures and their impact while introducing Shannon entropy as a metric to measure complexity of trinucleotide distributions.

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