Comprehensive Genomic Profiling for Childhood Oncology Research

Now you can combine the extensive DNA panel from Ion Torrent™ Oncomine Comprehensive Assay Plus with the broad RNA panel from the Oncomine™ Childhood Cancer Research Assay to cover an extensive range of variants and gene fusions.

The powerful solution enables genomic profiling of cancers affecting children and young adults. Since the driving genetic aberrations of these malignancies are different than those affecting adults, a specific and comprehensive panel is needed to advance childhood oncology research.  

Oncomine Comprehensive Assay Plus DNA Panel  

  • 500+ genes
  • Single-nucleotide variants (SNVs), insertions and deletions (indels), copy number variants (CNV)
  • Complex biomarkers: homologous recombination deficiency (HRD), tumor mutational burden (TMB), and microsatellite instability (MSI). 

Oncomine Childhood Cancer Research Assay RNA Panel  

  • Compiled by leading researchers and childhood oncologists
  • 97 gene fusion and gene expression targets
  • Almost 2000 fusion isoform variants

 

Oncomine Childhood Research Assay
RNA Panel gene targets

ABL1 
ABL2 
AFF3 
ALK 
BCL11B 
BCOR 
BCR 
BRAF 
CAMTA1 
CCND1 
CIC 
CREBBP 
CRLF2 
CSF1R 
DUSP22 
EGFR 
ETV6 
EWSR1 
FGFR1 
FGFR2 
FGFR3 
FLT3 
FOSB 
FUS 
GLI1 
GLIS2 
HMGA2 
JAK2 
KAT6A 
KMT2A 
KMT2B 
KMT2C 
KMT2D 
LMO2 
MAML2 
MAN2B1 
MECOM 
MEF2D 
MET 
MKL1 
MLLT10 
MN1 
MYB 
MYBL1 
MYH11 
MYH9 
NCOA2 
NCOR1 
NOTCH1 
NOTCH2 
NOTCH4 
NPM1 
NR4A3 
NTRK1 
NTRK2 
NTRK3 
NUP214 
NUP98 
NUTM1 
NUTM2B 
PAX3 
PAX5 
PAX7 
PDGFB 
PDGFRA 
PDGFRB 
PLAG1 
RAF1 
RANBP17 
RARA 
RECK 
RELA 
RET 
ROS1 
RUNX1 
SS18 
SSBP2 
STAG2 
STAT6
TAL1 
TCF3 
TFE3 
TP63 
TSLP 
TSPAN4 
UBTF 
USP6 
WHSC1 
YAP1 
ZMYND11 
ZNF384 
 
 

Gene Expression
BCL2 
BCL6 
FGFR1 
FGFR4 
IGF1R 
MET 
MYCN 
MYC 
TOP2A 

 

Optimized workflow for fast results

  • End-to-end solution, including informatics
  • From sample to report in 2–3 days, depending on sample type
  • Multiple sample types, including blood, bone marrow, and formalin-fixed, paraffin-embedded (FFPE) tissue 

 

cgp-workflow-2

Ordering Information

Panel SKU
OCA PLUS DNA + OCCRA RNA, MANUAL  A58010 
OCA PLUS DNA + OCCRA RNA, CHEF-READY A58011

 

 

 

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For Research Use Only.  Not for use in diagnostic procedures.